2 years of menopause menstruation return against endometrial cancer!

51-year-old this year, Liu aunt, menopause is 2 years, but at the beginning of this year and a half months she continuously appear irregular bleeding, although overtime is not much, but she very panic: why the "via" go and return to the hospital for a check?, Liu aunt had suffered from endometrial cancer!

Postmenopausal women of blood return more caution

Doctors advise, like Liu aunt age has been postmenopausal women, vaginal bleeding, irregular occurrence should be careful, it's best to go to a detailed inspection.

Because of bleeding often may be a symptom of certain malignant diseases. According to reports, if bleeding minimal, which lasted not long, 2 days ~ 3 days i.e. NET for postmenopausal endometrial bleeding resulting from falls or vaginitis; if the amount of bleeding, persistent net or recurrent vaginal bleeding, you should consider endometrial carcinoma.

Endometrial cancer risk factors are:

I. long-term continuous stimulation by estrogen to endometrial continuous thickening and increased cell deterioration, such patients may be because the ovaries, as long a few will produce this type of hormone of tumors, or suffering from many cystic ovary that ovulation abort and amenorrhea, endocrine changing and hormones.

Second, the long-term administration of a single drug, estrogen and progesterone is not attached to the drug class.

Third, the more fertilizer in General, and have high blood pressure, diabetes, unmarried or human suffering from chance or slightly higher.

As mentioned above, if you use only the "hormones", while taking estrogen is also in the body of the uterus, in the long term is to increase the risk of cancer, but if the uterus is removed, that does not have to worry about, such as uterine also, estrogen and progesterone should both.

The incidence of endometrial cancer

Endometrial cancer, also known as the incidence of cancer of the uterus, second only to cervical cancer, accounting for the total number of female cancer, accounting for 7% of the female reproductive tract cancer 20% ~ 30%, their high age 58-61-year-old, 80% occur in women over 50 years, the average age of 60 years or so.

Endometrial cancer treatment with surgery

Endometrial cancer therapy principles, should be based on the clinical stage, cancer cells differentiation, the patient was in a situation and other factors into consideration.

Because the vast majority of endometrial cancer is cancer that is not sensitive to radiation therapy, treatment with surgery, there are still other radiotherapy and chemotherapy and other drug treatment.

(1) surgery

At present has formed more consistency that most ⅰ and Ⅱ period endometrial cancer cured by surgery.

For a period of G1 cancer Ⅰ through hysterectomy plus double attachment for a cure.

ⅰ poorly differentiated Carcinoma (G2 and G3) to hysterectomy and bilateral attachment cutout effect in conjunction with radiotherapy than simple surgery as well.

When uterine cavity diameter > 10cm, also this combination therapy is appropriate.

II endometrial cancer treatment base with cervical cancer, i.e. rows of generalized hysterectomy with lymph node excision of the pelvis.

But now the best results are reported through in vitro and cavity radiation after hysterectomy for comprehensive treatment.

(2) radiation therapy

For the effects of radiotherapy and application methods are still controversial.

But it is generally believed that the first phase Ⅰ-level, non-invasive violations, simple operation. For the first stage poorly differentiated Carcinoma (Ⅱ and ⅲ), myometrial violations > 1/2, lymph, and II endometrial cancer, at present, the use of preoperative Endovascular Radium Therapy after hysterectomy and bilateral attachment cutout and postoperative adjuvant radiotherapy.

Treatment of stage I endometrial cancer also shall be based on the pathological differentiation, tumor invasion and metastasis of muscle depth, and the celiac exfoliated cells is positive, so consider irradiation treatment is appropriate to increase the cure rate.

In addition, radiotherapy or chemotherapy medicine used for elderly patients, surgery of appropriate and a few advanced taboo lesions associated with multiple organ involvement or unresectable tumor-induced bleeding of palliative care.

Patients with advanced cancer and recurrent cancer treatment: Ⅲ, ⅳ carcinoma is not completely removed by surgery, generally use radiation therapy (endovenous laser therapy plus radiotherapy) and chemotherapy.

(3) hormones and chemical treatment

As mentioned earlier, the progesterone can make Dysplasia of the endometrium into secretory stage or atrophic endometrium, which can cause endometrial adenomatous hyperplasia and adenoma of atrophy, reversed.

About 1/3 of patients with advanced or recurrent endometrial cancer patients on progesterone preparation effectively, especially lung metastases are best, about 35 patients with significant response. But within the pelvic recurrent or persistent lesions is not optimal.

Progesterone Therapy and other cytotoxic anticancer agent as palliative chemotherapy as a rather radical.

By far the most common PR agents have 17-hydroxy-progesterone or acid progesterone and megestrol acetate. Recently reported that estrogen antagonist on primary tumor to estrogen receptor-positive relapse retinopathy, or when progesterone treatment fails, the application of this drug.

Question about prognosis: all malignant tumors are body organ a cell mutation, rapid multiplication (reason not clear).

Once you become a cancer cell mutations. This process to a number of years a cell through 30 generations of double into a substantive 1g to tumor cells, containing a number 10. The greater the number of tumor cells, treatment, prognosis is poor, the more difficult, so early detection and early treatment. First surgical resection of the tumor as possible, the prognosis is good.

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(Practice editing: xiujie)

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